Janey Fabre knows she isn't the average thirty-something. After all, she has found herself stalking her ex-boyfriend on more than one occasion. But when she s group therapy, she is convinced that the other women she meets are ten times loopier than she is. Suzanna prefers the company of her dog to human beings. Laura is a record-breaking gold medalist in the one-night-stand Olympics. And Bethany, a forty-year-old divorcée, still lives with her mother. Not to mention Valentine, a painfully shy beauty who binges on DoveBars; Ivy, a sweet-talking southern belle who binges on Botox; and Natasha, who wears a face mask to protect herself against unseen airborne pathogens.

Over time, Janey and the girls concoct an outrageous scheme for asserting themselves, and suddenly they're embroiled in a reckless and exhilarating misadventure that wreaks havoc on their lives but ultimately illuminates the power of loyalty and the true meaning of friendship.